Yay this makes me so happy. Thanks for listening. And thank your wife for me for influencing you haha.
My thoughts on the main beneficial effects we are looking for would be:
- the reduction of fine lines and wrinkles
- reduction of skin laxity and/or skin atrophy
- texture improvement
- increase of collagen
- increase of elastin
Things that it might still impact, but we might need to limit what the focus is:
- reduction of dark circles
- does it affect moisture/hydration levels?
- does it affect pigmentation and irregularities?
- I would consider other potential positive side effects that might still occur. For instance Tretinoin was created for acne, but has a significant improvement on wrinkles. I’m assuming that clearing up acne or eczema or even erythema etc might be a secondary benefit if it is increasing cell turnover. It seems like research on growth factors saw this too.
At a larger level I guess I’d say the goal would be to decrease photoaged skin because that’s a culmination of all those things.
I’m also curious about benefits over long term use:
- does it have an effect on senescent cells
- preventing facial bone and volume loss
- could it be a stand alone treatment to collagen banking
Some things I would think about:
In regards to the mask prototype itself, are you thinking of it being like a few coils that would tape to your face or similar to a RLT mask?
I’m not sure if there is a way to create it without being taped to your face or having tape on it. Seems like the above chain where someone used glasses as a skeleton is an interesting approach on thinking about it.
In my experience wearing it on my face after doing my skincare makes the tape get gross/need to be switched out frequently. And I would prefer not to tape it to my face because sometimes the tape irritates my skin or peels it. You also wouldn’t be able to use it after a skin treatment say like microneedling because your face is essentially an open wound for a week. But it would be incredibly helpful to speed up healing after with a mask.
I would maybe get an omnilux or Dr Dennis gross to see how it’s built or get inspiration from the structure. I don’t have a mask I use a panel, but I feel like my face is kind of small and am wonder how the sizing works for everyone so I think size would be something to consider.
I’d also think about factors like:
- people with an established top tier skincare routine
- If people use Botox
- people that have other skincare treatments done and keep up with it
-(microneedling, lasers, red light therapy, microcurrent therapy)
- topical ingredients that already have regenerative properties like Tretinoin, actives, growth factors, and exosomes.
I would take into consideration that either people that have done none of those things might have a higher baseline for improvement or the opposite, the quality of their progress might be really impressive compared to those that have not. And they just amplify the use of pemf. For instance a symbiotic relationship like people getting Botox and then using actives to tackle removing fine lines.
Ways to measure:
- photo progress
- the Fitzpatrick wrinkle and degree of elastosis scale
- potentially using an independent evaluator
- there are devices that measure skin elasticity, I’m not sure what would be best though. Or right for this experiment.
- I wonder if the device this guy uses in this video is legit and could be used
- it looks like there’s new technology that measures skin hydration through your phone
- patient questionnaires (this seems to be an added step of skincare studies)
- In the future, maybe consider biopsy to see at a deeper level. This study saw an improvement in the quality of collagen in the papillary layer and an increase of elastic fibers in the upper dermis when they did biopsies.
- I’d maybe look at skincare rejuvenation studies on how they went about their study and measured it.